The combination of omega-3s, vitamin D, and physical exercise may slow biological aging by 3 to 4 months over a 3-year period.

noli's read

This advice is based on research exploring epigenetic clocks, which measure biological aging at the DNA level. A study published in Nature Aging (2023), using observational data and methylation marker analysis, suggested an association between supplementation with specific nutrients and a reduction in epigenetic age. It is established that omega-3s and vitamin D play a protective role in inflammation and cellular health, while exercise is a major driver of longevity. However, assigning such a precise figure (3-4 months) to a combined intervention remains a complex extrapolation, as the mechanisms are multifactorial and vary greatly between individuals. Although the idea is scientifically plausible and supported by mechanistic evidence, it should be noted that studies on biological clocks are still relatively recent. The claim therefore tends to simplify a biological correlation into a linear measurement of time, which is technically difficult to isolate with such exactitude.

the sources

1. 1NIH Office of Dietary Supplements 2026
2. 2Manson JE et al. 2019
3. 3Bhatt DL et al. 2019
4. 4NIH Office of Dietary Supplements 2026
5. 5Lauersen JB et al. 2014