Significantly increasing the daily dose of creatine, beyond typical recommendations, is said to improve mental alertness, mental endurance, and cognitive faculties, particularly to counter persistent fatigue.

noli's read

The community shows marked enthusiasm for high dosages (10-15g), although current scientific evidence mainly supports a standard dose of 3 to 5g per day for muscle and cognitive health (meta-analysis, Journal of the International Society of Sports Nutrition). While creatine is well-documented for supporting cerebral energy metabolism, particularly in cases of sleep deprivation or cognitive stress (narrative review, Experimental Gerontology), the efficacy and safety of a tripled dosage in healthy individuals remain poorly studied. The observed effect could result from an initial deficiency (e.g., a meat-poor diet) or a placebo effect, rather than a biological necessity for such a dose. It is important to note that the body has a limited saturation capacity; the surplus is generally excreted by the kidneys, although this can cause water retention in some. The consensus here is very favorable toward personal experimentation, although some members cautiously call for seeking the root cause of the fatigue.

the sources

1. 1NIH Office of Dietary Supplements 2026
2. 2r/Supplements