The community suggests that taking nicotinamide (a form of vitamin B3) is an effective and safe strategy for significantly reducing the risk of developing certain skin cancers.

noli's read

The claim is based on a pivotal study published in the New England Journal of Medicine (RCT), which demonstrated that oral intake of 500 mg of nicotinamide twice daily reduced the incidence of new non-melanoma skin cancers by 23% in high-risk individuals. The figure of 54% mentioned in the thread appears to refer to a specific reduction in squamous cell carcinomas among patients with a history of the condition, which represents a partial interpretation of the overall data. While the protective effect is scientifically supported for this target population, there is no equivalent evidence for the general population without such a history. It is crucial to note that nicotinamide differs from niacin (nicotinic acid); the latter does not provide the same dermatological benefits and may cause side effects such as flushing. The community shows a strong positive consensus, validating the use of this vitamin as a routine supplement for skin health.

the sources

1. 1r/Supplements