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Andrew Huberman@huberman-protocolsweb

Prendre du bore pour maximiser la disponibilité de la testostérone active dans …

what it claims

Take between 5 and 12 mg of boron daily as a dietary supplement to lower SHBG levels and thereby optimize the availability of free testosterone in the body.

mixed

The idea of regulating the SHBG protein to release active testosterone using boron is based on intriguing biological foundations. A pilot clinical study conducted by Naghii et al.

noli's read

The idea of regulating the SHBG protein to release active testosterone using boron is based on intriguing biological foundations. A pilot clinical study conducted by Naghii et al. (2011) on 8 men did indeed show that taking 10 mg of boron per day reduced SHBG and increased free testosterone after only one week. However, this preliminary work, which lacked a placebo group and used a very small sample size, does not allow for conclusions regarding a lasting or systematic effect. Conversely, a more robust randomized controlled trial (RCT) conducted by Green and Ferrando (1994) on athletes revealed no significant change in testosterone after seven weeks of supplementation. Finally, clinical observation data suggest that at this dose, boron may also raise estrogen levels, which could disrupt the balance sought for male vitality. The actual long-term effect of this strategy therefore remains highly uncertain, although boron remains a valuable daily micronutrient.

the sources

Claimed by Andrew Huberman. Noli grades the claim, never the person.

Decoded by Noli · July 13, 2026 · the original post

What the graded evidence says

Effect: CV events, high-risk patients on high-dose EPA (REDUCE-IT) — -25% relative (high-risk only)
Measured on: REDUCE-IT: 8,179 statin-treated high-risk patients

Strong for a specific medical use; modest for everyday wellness.

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holds upPaul McNally

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mixedThebiohackingrn

Noli has read similar claims

Other advice in the Register that leans on the same research.

To support heart, brain, and immune system health, it is recommended to use a high-quality omega-3 supplement (with transparent purity testing) to compensate for insufficient intake in the modern diet.

holds upSteph Grasso, MS, RD

Get your vitamin D and triglyceride levels tested at the onset of menopause, as the drop in estrogen naturally increases cardiovascular risk. To address this, it is recommended to supplement with vitamin D, vitamin K2 (to guide calcium toward the bones rather than the arteries), and 2g of EPA-rich omega-3s to limit inflammation and regulate blood lipids.

holds upMary Claire Haver, MD

Omega-3s (especially in EPA/DHA forms) are essential fats often lacking in our modern diet. Supplementing allows, in a scientifically proven manner but without miracles, for the reduction of inflammatory stress, the acceleration of physical recovery, the support of cardiac vitality, and the stabilization of mood.

holds upGreg /Major Mouvement ( kiné à bretelles )

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