Get your vitamin D and triglyceride levels tested at the onset of menopause, as the drop in estrogen naturally increases cardiovascular risk. To address this, it is recommended to supplement with vitamin D, vitamin K2 (to guide calcium toward the bones rather than the arteries), and 2g of EPA-rich omega-3s to limit inflammation and regulate blood lipids.

noli's read

The claim regarding the rise in triglycerides is based on a rigorous observational study published in Oxford Academic (2025) involving two highly active indigenous populations (the Tsimané and the Mosetén), confirming that for an identical lifestyle, the hormonal transition increases the risk of rising blood fats by a factor of 2.5. The direct impact of the drop in estrogen on lipid balance is, moreover, widely documented by long-term cohort studies. Regarding supplementation, a 2023 meta-analysis of randomized controlled trials (RCTs) confirms that omega-3s significantly decrease triglycerides in menopausal women. The recommended intake of 2g of EPA-rich omega-3s is entirely consistent with the guidelines of institutions like the American Heart Association for supporting cardiovascular health. As for the vitamin D and K2 duo, meta-analyses of RCTs validate the benefit of K2 for preserving bone strength and density post-menopause. However, the claim that K2 prevents calcium from depositing in the arteries relies primarily on a promising theoretical model (the 'calcium paradox') but still lacks direct and indisputable clinical evidence in humans. Finally, the suggestion to have your vitamin D and lipid levels measured through a simple check-up remains an excellent preventative practice.

the sources

1. 1NIH Office of Dietary Supplements 2026
2. 2Manson JE et al. 2019
3. 3NIH Office of Dietary Supplements 2026
4. 4Bhatt DL et al. 2019
5. 5Khan SU, Lone AN, Khan MS, et al. 2021
6. 6Liao Y, Xie B, Zhang H, et al. 2019