noli.

Register

Paul Saladino, MD@paulsaladinomdInstagram

Animal fats > seed oils Some people like to say “there no studies suggesting that seed oils are harmful”… But

… more

what it claims

Swapping seed oils for animal fats isn't backed by the best current evidence: in studies that hold calories constant, replacing saturated fat with polyunsaturated fat (seed oils) shows neutral-to-better results on LDL and cardiovascular risk — not the reverse.

overstated

Stripped of the "welcome to the remembering" framing, the claim is: there's an overwhelming number of controlled human studies showing seed oils are harmful.

noli's read

Stripped of the "welcome to the remembering" framing, the claim is: there's an overwhelming number of controlled human studies showing seed oils are harmful. The cited PMIDs are almost all from the 1970s-1990s and are mostly mechanistic or animal studies on lipid oxidation, not modern clinical trials on real-world dietary intake. Against that, recent systematic reviews say the opposite on the central point (inflammation): two meta-analyses of controlled trials (Journal of the Academy of Nutrition and Dietetics 2012, 15 trials; Food & Function 2017, 30 trials, 1,377 subjects) find no significant effect of linoleic acid on blood inflammatory markers, and a 2025-2026 Frontiers in Nutrition review concludes that most human evidence supports a favorable role for linoleic acid in cardiometabolic health. The Sydney Diet Heart Study (1978), often cited by this camp after its controversial 2010s reanalysis, is considered methodologically unreliable by current literature. The "animal fats > seed oils" advice doesn't hold up against the strongest evidence available today.

the sources

No named source held this one up — that absence is part of the verdict.

Claimed by Paul Saladino, MD. Noli grades the claim, never the person.

Decoded by Noli · August 3, 2026 · the original post

Paul Saladino, MD in the Register4 claims gradedSee their record →

More from Paul Saladino, MD

Others on this

Noli, a firefly holding its lantern, at rest

Seen something like this? Send it to Noli.

Paste any health post from TikTok, Instagram, YouTube or X — or the advice itself, if someone just told you. About ten seconds, no account needed.