Regularly and intensely engage your muscles (if only for 4 minutes a day) or practice strength training to release myokines (such as IL-6), powerful natural molecules that optimize the functioning of the entire body and promote vitality.

noli's read

The idea that muscles act as a 'pharmacy' via myokines is based on a solid scientific foundation. The role of interleukin-6 (IL-6) as an anti-inflammatory molecule released during exercise was highlighted by the work of researcher Bente Klarlund Pedersen (physiological studies and reviews), showing that it helps harmonize our defenses. Regarding the 4 minutes of intense daily effort, the creator relies on a large observational study conducted by Pr. Emmanuel Stamatakis (published in Nature Medicine in 2022). This research shows that brief bursts of intense daily activity (such as brisk walking) are associated with a nearly 30% reduction in all-cause mortality. Finally, the 174% strength gain in seniors comes from a pioneering interventional clinical trial by Dr. Maria Fiatarone (published in the JAMA in 1990). This protocol proved that even late-life strength training dramatically improves vitality and autonomy. Thus, all of the creator's claims are rigorously validated by science.

the sources

1. 1Hoffmann C, Weigert C 2017
2. 2Stamatakis E et al. 2022
3. 3Stamatakis E et al. 2023