Having an omega-3 index of 8% or higher is associated with an increased life expectancy of 5 years compared to an index of 4% or less, which can be achieved through omega-3 supplementation.

noli's read

This advice is based on observational cohort studies, notably those using data from the Framingham Offspring Cohort. This research shows a robust correlation between higher levels of EPA and DHA in red blood cells (the omega-3 index) and a reduction in all-cause mortality risk. The estimate of an approximately 5-year increase in life expectancy is a statistical extrapolation derived from these observations. It is important to note that these studies show an association and not a direct causal link: higher omega-3 levels may reflect an overall healthier lifestyle (diet, physical activity). Although supplementation can effectively increase the omega-3 index, asserting that it will mechanically extend life by 5 years is a bold interpretation, as long-term interventional clinical trials specifically designed to measure increases in lifespan are complex and rare.

the sources

1. 1NIH Office of Dietary Supplements 2026
2. 2Manson JE et al. 2019
3. 3Bhatt DL et al. 2019