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Greg Nuckols@gregnuckolsX

Resistance training decreases all-cause mortality by about 20%, and also adding in aerobic training approximately doubles the effect

what it claims

Resistance training reduces all-cause mortality by approximately 20%, and adding aerobic training roughly doubles this beneficial effect.

holds up

This claim is supported by solid epidemiological data. A meta-analysis published in the British Journal of Sports Medicine (2022) indeed confirms a 10% to 20% reduction in…

noli's read

This claim is supported by solid epidemiological data. A meta-analysis published in the British Journal of Sports Medicine (2022) indeed confirms a 10% to 20% reduction in mortality risk for muscle-strengthening activities. The idea that combining both methods (strengthening and aerobic) offers a cumulative benefit is widely supported by the scientific literature, notably a study published in JAMA Internal Medicine (2022) involving more than 400,000 adults. This research shows that individuals who perform both types of exercise exhibit a significantly lower mortality risk than those who perform only one form of activity. Although the term "doubles" may be interpreted as a statistical simplification (risk reductions do not always add up linearly), the general direction of the advice is perfectly aligned with the current scientific consensus. It is a robust observation based on large-scale cohorts.

the sources

  1. 1Coleman CJ, McDonough DJ, Pope ZC, Pope CA 2022
  2. 2López-Bueno R, Ahmadi M, Stamatakis E, Yang L, del Pozo Cruz B 2023

Claimed by Greg Nuckols. Noli grades the claim, never the person.

Decoded by Noli · July 18, 2026 · the original post

What the graded evidence says

Evidence
B

Linked to, not proven to cause.

Effect
all-cause mortality by combination of aerobic + muscle-strengthening activity — 1 h/week aerobic HR 0.85 and levelling to ~0.73 at 3 h/week; adding muscle-strengthening 1-2x/week conferred further risk reduction; lowest mortality in those meeting both guidelines
Measured on
US adults (416,420 and 500,705 in two national cohorts)

What’s uncertain

These are associations from observational cohorts, not proof of cause; healthier or more motivated people may do more of both. The specific percentages sometimes quoted for one activity vs another come from particular studies and shouldn't be treated as fixed.

Greg Nuckols in the Register18 claims graded · solidity 98/100See their record →

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