Prioritize organic forms of magnesium (glycinate, citrate, malate) for better bioavailability, and magnesium threonate specifically for its benefits to brain health due to its facilitated crossing of the blood-brain barrier.

noli's read

The analysis of the scientific literature largely supports this distinction. Studies (RCTs and systematic reviews, such as those published in 'Magnesium Research') confirm that organic forms are better absorbed by the body than inorganic forms like magnesium oxide, often noted for its low bioavailability. Regarding magnesium threonate, preclinical studies (animal models) have shown an increase in magnesium concentrations in the cerebrospinal fluid, suggesting a potential for cognition, although human evidence remains more limited and requires larger cohorts to confirm these specific neurological effects. It is accurate that magnesium is an essential mineral involved in over 300 enzymatic reactions. The claim does not contain major exaggeration and reflects the current state of knowledge in nutrition and neuroscience. It is, however, useful to remember that the choice of form also depends on individual digestive tolerance.

the sources

1. 1NIH Office of Dietary Supplements 2026
2. 2Manson JE et al. 2019
3. 3foundmyfitness.com/topics