Magnesium is the "master mineral" essential for the proper functioning of the body, as it is involved in 800 different biochemical reactions.

noli's read

The figure of 800 reactions is frequently cited in specialized literature, although some conservative sources point instead to 300 to 600 magnesium-dependent enzymes, making Siim Land's figure a high but plausible estimate depending on the definition of cofactors. The importance of magnesium for mitochondrial, cardiovascular, and metabolic function is firmly established by numerous scientific reviews (e.g., meta-analyses on cardiovascular health and glycemic regulation). The impact on mental health and well-being is supported by observational evidence and some clinical trials, notably regarding stress management and sleep quality, although effects vary according to the forms of magnesium used. It is not an exaggeration to describe this mineral as a biological pillar, as it is ubiquitous in the metabolism of ATP (cellular energy). What is sometimes missing in this type of communication is nuance regarding bioavailability: not all forms of magnesium are equivalent for targeting specific functions such as the brain or muscles. In summary, the assertion is scientifically grounded, although the title of "master mineral" is a popularized simplification of its essential role as a cofactor.

the sources

1. 1NIH Office of Dietary Supplements 2026