Inhibiting or eliminating interleukin-11 (IL-11) improves health and extends lifespan by up to 24% in mice.

noli's read

This advice is based on a study published in the journal Nature (2024), conducted by researchers at the MRC Laboratory of Medical Science. The evidence comes from animal experimentation (mouse models), showing that by blocking this inflammatory protein, a reduction in metabolic aging and age-related diseases is observed. What holds true is the strong link between IL-11, chronic inflammation (sometimes called 'inflammaging'), and functional decline in mice. However, it is important to note that this is preclinical research; extrapolating these results directly to humans is a major step that has not yet been validated by clinical trials. The potential exaggeration lies in the immediate promise of longevity for humans, while therapies targeting IL-11 are in the development stage. There is currently no evidence that this mechanism produces similar effects safely in humans over the long term.

the sources

No named source held this one up — that absence is part of the verdict.