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Mark Hyman, M.D.@drmarkhymanInstagram

Your liver does a lot more than digest food. One of its most underappreciated jobs is clearing excess

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what it claims

Consume soluble fiber to help the liver eliminate bile acids, which would facilitate the excretion of excess cortisol, reduce stress, lower LDL cholesterol, and stabilize blood glucose.

mixed

The metabolism of cortisol by the liver is a well-established physiological mechanism.

noli's read

The metabolism of cortisol by the liver is a well-established physiological mechanism. Likewise, numerous meta-analyses of randomized controlled trials (RCTs) confirm that soluble fibers trap bile acids in the intestine, which effectively reduces LDL cholesterol and stabilizes blood glucose. However, the idea that an 'overloaded' liver struggles to eliminate cortisol in a healthy person is a conceptual simplification common in the wellness world. Furthermore, asserting that the elimination of bile acids by fiber directly decreases cortisol recirculation is an extrapolation without direct scientific evidence. While a randomized controlled trial (RCT) conducted by Schmidt et al. (2015) shows that supplementation with soluble prebiotic fibers does indeed decrease morning cortisol, this effect is scientifically attributed to the modulation of the microbiota and the gut-brain axis, rather than to a mechanical trapping of the stress hormone in the digestive system.

the sources

  1. 1Reynolds A et al. 2019
  2. 2Jovanovski E et al. 2019

Claimed by Mark Hyman, M.D. Noli grades the claim, never the person.

Decoded by Noli · July 13, 2026 · the original post

What the graded evidence says

Evidence
A-

Linked to, not proven to cause.

Effect
all-cause mortality, high vs low fibre intake — -15-30%
Measured on
WHO-commissioned series: 185 prospective studies + 58 trials

What’s uncertain

Huge and consistent, but observational + trials on intermediate outcomes.

Mark Hyman, M.D. in the Register140 claims graded · solidity 73/100See their record →

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