Test your lipoprotein (a) or Lp(a) level at least once—a genetic heart health risk factor that affects 1 in 5 people and varies little with lifestyle—in order to adjust other modifiable wellness parameters if necessary.

noli's read

Mark Hyman wisely highlights lipoprotein (a) or Lp(a), a key but often overlooked player in heart health. The assertion that Lp(a) is a potent genetically determined risk factor affecting approximately 20% of the population is solidly validated by research, notably by a consensus from the European Atherosclerosis Society (EAS). Furthermore, American Heart Association (AHA) guidelines confirm that a one-time screening in a lifetime is strongly advised, as this parameter is not measured during routine exams. Large-scale observational studies also confirm that this level is more than 90% determined by genetics, making it unresponsive to changes in diet or physical activity. Conversely, the suggestion to 'monitor' this level regularly via a platform is scientifically superfluous, as a single test in one's lifetime is generally sufficient to establish one's profile. The true value lies in identifying this factor once and for all to best personalize the rest of one's lifestyle.

the sources

1. 1Kronenberg F, Mora S, Stroes ESG, et al. 2022