Aging is caused by a loss of epigenetic information; it is therefore possible to 'reboot' the body and reverse biological age through genetic and chemical interventions.

noli's read

David Sinclair relies on the information theory of aging, suggesting that our cells lose the ability to read their own DNA code over time. Research, notably published in 'Cell' (2020) by the Sinclair lab, shows that epigenetic reprogramming (via Yamanaka factors) can restore vision in aged or glaucomatous mice, which constitutes a laboratory proof of concept (animal study). However, extrapolating these results to humans is a major simplification. While epigenetic mechanisms play a key role in aging, we lack rigorous clinical trials (RCTs) in humans demonstrating systemic age reversal. Claiming that we can 'reboot' the human body like software remains a speculative hypothesis at this stage. Scientific caution requires distinguishing the fascinating potential of cell biology from current clinical applications.

the sources

No named source held this one up — that absence is part of the verdict.