Your thoughts directly influence your biology: mental stress triggers the production of stress hormones, while a calm state of mind promotes the release of restorative substances.

noli's read

This advice is based on the concept of the mind-body connection, a field extensively studied in psychoneuroimmunology. It is scientifically established that perceived stress activates the hypothalamic-pituitary-adrenal axis, leading to the release of cortisol and adrenaline, which is documented by numerous observational and clinical studies (e.g., the work of Robert Sapolsky). The idea that positive mental states promote 'healing' is supported by research showing that relaxation can reduce systemic inflammation, as indicated by certain meta-analyses on mindfulness interventions (e.g., JAMA Internal Medicine). However, the term 'pharmacy' is a metaphor that can be interpreted excessively; while the state of mind influences well-being, it does not replace established medical treatments for serious pathologies. The direct link between a specific thought and a precise biochemical compound is often simplified in this discourse to make it accessible. In short, the mind's ability to modulate our physiological response is a fact, but the extent of this control is nuanced by genetic and environmental factors.

the sources

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5. 5Dewar M, Alber J, Cowan N, Della Sala S. 2014
6. 6Weng L, Yu L, Rong J, et al. 2025