The decline of physiological markers related to health and aging (collagen, VO2 max, melatonin, bone density) begins as early as the twenties or thirties, well before most people are concerned about them.

noli's read

The claim that biological functions begin to decline early is widely supported by scientific literature. The decrease in VO2 max after 20-25 years is well-documented by observational studies on physiological aging. Regarding collagen, research (notably published in 'Dermato-Endocrinology') confirms a decrease in cutaneous synthesis starting at age 20. Bone density does indeed reach a peak around age 30, a consensus datum in rheumatology. A drop in melatonin after puberty is also observed, although its clinical impact on overall health remains an active subject of research. However, presenting these declines as inevitable can be nuanced: lifestyle (exercise, nutrition) can significantly slow the rate of these losses. These are not pathologies, but natural trajectories that can be positively influenced by early healthy habits.

the sources

1. 1Mandsager K, Harb S, Cremer P, Phelan D, Nissen SE, Jaber W 2018
2. 2Watson SL, Weeks BK, Weis LJ, Harding AT, Horan SA, Beck BR 2018