Receiving hugs or being in a romantic relationship can modify your gene expression by activating repair genes and deactivating those linked to inflammation.

noli's read

Dr. Hyman is highlighting a fascinating field of research here called social epigenetics. It is established that positive social interactions and emotional support can influence biology, notably by regulating stress hormones like cortisol. Studies, such as those published in 'Psychoneuroendocrinology' (observational studies and reviews), show that strong social support is associated with a decrease in systemic inflammatory markers, such as C-reactive protein. The idea that this modifies gene expression is scientifically grounded: research (notably the work of Steve Cole on leukocytes) indicates that social isolation can activate pro-inflammatory gene pathways, while positive connections can modulate them. However, the term 'activating repair genes' is a popularized simplification of a complex and multifactorial biological mechanism. While the link between relational well-being and biology is solid, presenting this as a direct 'on/off' switch is a slightly exaggerated interpretation of nuanced cellular processes. This is a mechanism of influence rather than a direct genetic transformation.

the sources

1. 1Holt-Lunstad J, Smith TB, Layton JB. 2010
2. 2Holt-Lunstad J, Smith TB, Baker M, et al. 2015