Never inject growth factors directly into the face to avoid the risk of deforming and recurring fatty growths. Reserve growth factors for superficial skincare and prioritize only proven injections such as your own tissues (PRP, fat), hyaluronic acid, Sculptra, or facial expression modulators.

noli's read

The creator rightly warns against the direct injection of growth factors, an unregulated practice that can cause serious long-term aesthetic deformities. This alert is based on solid facts: an observational study published in the specialized journal *Aesthetic Plastic Surgery* confirms that these injections lead to the formation of small, benign fatty tissue masses that are very difficult to remove, with a recurrence rate of 37.5% after intervention. In the field of skin wellness, these proteins act as messengers that stimulate cellular regeneration, which explains why their direct injection can cause uncontrolled local proliferation. Conversely, their superficial application via serums or after gentle microneedling remains a safe and validated method to support skin radiance. Finally, the list of alternatives proposed by the creator effectively corresponds to the safest and most well-regulated remodeling options recognized by industry experts.

the sources

No named source held this one up — that absence is part of the verdict.