Hormone therapy for menopause must be personalized and adapted to each woman, as the dose required to relieve immediate symptoms (such as hot flashes or sleep disturbances) is not necessarily the same as that required to protect long-term health (such as bone strength), as hormone absorption varies from one person to another.

noli's read

The observation that menopause affects overall well-being (sleep, bone strength, hair quality) is solidly validated by research. For example, the guidelines from the North American Menopause Society (NAMS, expert consensus) confirm that hormone therapy helps maintain bone strength and relieve intimate discomfort. The assertion that dosages must be personalized is also supported: the British Menopause Society (BMS, clinical practice recommendations) advocates for a tailored approach, adjusted according to individual tolerance. Regarding the idea that a dose that eases symptoms does not necessarily provide long-term protection, reviews of randomized clinical trials (RCT) show that even very low doses of hormones are generally sufficient to preserve bone density. Saying that feeling well does not mean being protected is therefore slightly exaggerated, as the protective effect on the skeleton is activated at even the lowest clinical dosages. Nevertheless, the individual variability of hormone absorption depending on the format used (transdermal or oral) is a well-documented biological fact that fully justifies personalized follow-up.

the sources

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