Andrew Huberman@huberman-protocolsweb

Prendre du Fadogia Agrestis pour stimuler la production endogène de testostérone.

what it claims

Consume Fadogia Agrestis (425 mg per day) to stimulate testosterone production, using cycling (for example, 8 weeks of use followed by 2 weeks off) to prevent risks of toxicity.

overstated

The idea that Fadogia Agrestis stimulates testosterone is based on an experimental study in rodents (Yakubu et al., 2005) that observed a significant increase in this hormone.

noli's read

The idea that Fadogia Agrestis stimulates testosterone is based on an experimental study in rodents (Yakubu et al., 2005) that observed a significant increase in this hormone. However, there are currently no clinical studies in humans to confirm these effects on our own vitality. The specific dosage of 425 mg per day is therefore a theoretical extrapolation that is not supported by any direct evidence in humans. Regarding safety, animal research (notably Yakubu et al., 2008) indicates risks of damage to the liver, kidneys, and reproductive functions during prolonged use or at high doses. The recommendation to 'cycle' intake to limit these risks is a common-sense strategy, but it has not been scientifically validated in humans. Thus, while the potential of this plant for our hormonal balance is promising in animals, the efficacy and safety of this protocol remain largely unproven in humans.

the sources

Claimed by Andrew Huberman. Noli grades the claim, never the person.

Decoded by Noli · July 13, 2026 · the original post

What the graded evidence says

Effect: CV events, high-risk patients on high-dose EPA (REDUCE-IT) — -25% relative (high-risk only)
Measured on: REDUCE-IT: 8,179 statin-treated high-risk patients

Strong for a specific medical use; modest for everyday wellness.

Noli has read similar claims

Other advice in the Register that leans on the same research.

To support heart, brain, and immune system health, it is recommended to use a high-quality omega-3 supplement (with transparent purity testing) to compensate for insufficient intake in the modern diet.

holds upSteph Grasso, MS, RD

Get your vitamin D and triglyceride levels tested at the onset of menopause, as the drop in estrogen naturally increases cardiovascular risk. To address this, it is recommended to supplement with vitamin D, vitamin K2 (to guide calcium toward the bones rather than the arteries), and 2g of EPA-rich omega-3s to limit inflammation and regulate blood lipids.

holds upMary Claire Haver, MD

Omega-3s (especially in EPA/DHA forms) are essential fats often lacking in our modern diet. Supplementing allows, in a scientifically proven manner but without miracles, for the reduction of inflammatory stress, the acceleration of physical recovery, the support of cardiac vitality, and the stabilization of mood.

holds upGreg /Major Mouvement ( kiné à bretelles )

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