Consume between 1 and 2 g of combined EPA and DHA daily (in the form of high-quality fish oil) to support brain function and soothe anxiety.

noli's read

The role of omega-3s for mental well-being rests on solid yet nuanced scientific foundations. Regarding the management of stress and anxiety, a major meta-analysis of 19 randomized clinical trials published in 2018 in JAMA Network Open (Su et al.) shows that a high intake (up to 2 g of EPA/DHA) is indeed associated with a notable reduction in internal tension. For cerebral vitality, an observational study of the ALFA cohort (2025) confirms that high blood levels of DHA are correlated with better long-term preservation of thinking skills. However, randomized controlled clinical trials, such as the one conducted in 2026 by the University of Southern California (USC) using 2 g of DHA, do not show improvement in memory or mental clarity in healthy adults. An analysis by the platform Examine.com (2022) also notes that the cognitive benefits of supplements primarily target individuals already experiencing mild impairments. In short, Andrew Huberman’s dosage is entirely relevant for soothing the mind, but the preventive shield effect on a brain that is already in peak condition is sometimes overestimated.

the sources

1. 1NIH Office of Dietary Supplements 2026
2. 2Manson JE et al. 2019
3. 3Bhatt DL et al. 2019
4. 4Khan SU, Lone AN, Khan MS, et al. 2021
5. 5Liao Y, Xie B, Zhang H, et al. 2019
6. 6hubermanprotocols.com (fan reference guide)