Circadian clock disruption accelerates biological aging by impacting key cellular processes such as inflammation, mitochondrial health, autophagy, and microbiota balance.

noli's read

The creator relies on a solid scientific review (PMID: 36583849, review published in *Science*) that explores the complex link between circadian rhythms and aging. The research confirms that our internal clocks effectively regulate crucial metabolic and cellular processes, and that their desynchronization is correlated with numerous markers of aging. It is scientifically established that circadian disruption, for example through irregular sleep or inappropriate light exposure, can weaken these mechanisms. The link to chronic inflammation and mitochondrial function is supported by strong evidence from animal models and observational human studies. While the phrase 'affects virtually all aspects' may seem broad, it accurately reflects the current systemic view of chronobiology. The analysis is therefore highly consistent with the current state of science, highlighting the importance of regularity for cellular longevity.

the sources

No named source held this one up — that absence is part of the verdict.