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Peter Attia, M.D.@peterattiamdInstagram

The most common mistakes people make starting keto | Dominic D’Agostino, Ph.D. This clip is from episode #

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what it claims

To optimize the ketogenic diet, it is crucial to prioritize sufficient protein intake to preserve muscle mass and to approach ketone supplementation with caution.

holds up

The recommendation to maintain adequate protein intake while on a ketogenic diet is supported by studies showing that excessive protein restriction can impair the maintenance of…

noli's read

The recommendation to maintain adequate protein intake while on a ketogenic diet is supported by studies showing that excessive protein restriction can impair the maintenance of lean body mass, a point validated by systematic reviews on protein metabolism (type: meta-analysis/review). The idea that ketosis may modulate NAD levels is an area of active research, although evidence in humans remains preliminary compared to animal models (type: observational/mechanistic). Regarding the use of the ketogenic diet for psychiatric disorders, such as anorexia, the subject is promising but is still at the stage of case studies or pilot trials, which calls for great caution (type: observational). Finally, the warning regarding ketone supplementation is consistent with current literature, which highlights a lack of consensus on optimal dosages and long-term safety (type: expert opinion/literature review). The content avoids excessive generalizations and clearly distinguishes metabolic benefits from emerging therapeutic applications.

the sources

  1. 1Morton RW, Murphy KT, McKellar SR, et al. 2018
  2. 2Leidy HJ, Clifton PM, Astrup A, et al. 2015

Claimed by Peter Attia, M.D. Noli grades the claim, never the person.

Decoded by Noli · July 18, 2026 · the original post

What the graded evidence says

Evidence
B+
Effect
fat-free mass gain (resistance training) and appetite/satiety — +0.30 kg fat-free mass with protein supplementation (95% CI 0.09-0.52), plateau at ~1.62 g/kg/day; higher protein meals reliably increase satiety vs equal-calorie lower-protein meals
Measured on
healthy training adults; weight-loss and weight-maintenance adults

What’s uncertain

More protein past roughly 1.6 g/kg/day doesn't add much for muscle or fullness. The satiety edge is real but modest, not a magic appetite switch.

Peter Attia, M.D. in the Register72 claims graded · solidity 93/100See their record →

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