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Brad Stanfield@bradstanfieldmdX

The new "high protein = BAD" study needs some context: - overnight biomarker study involving 23 people - liquid diet using a "Boost Plus"

what it claims

Studies suggesting that high protein intake is harmful should be viewed with perspective, as they are often based on limited methodologies (small sample sizes, use of ultra-processed sugary foods) rather than evidence of intrinsic protein toxicity.

mixed

Brad Stanfield's analysis correctly highlights that study quality is paramount when interpreting nutritional risks.

noli's read

Brad Stanfield's analysis correctly highlights that study quality is paramount when interpreting nutritional risks. Large-scale observational studies, such as the meta-analysis published in the BMJ in 2020, have shown that total protein intake is actually associated with a reduction in all-cause mortality risk. Conversely, more recent research suggests that very high protein intakes could, via cellular mechanisms (such as those related to the amino acid leucine), influence certain cardiovascular health markers. However, the current consensus in the wellness field is that protein is essential for preserving muscle mass, particularly with age. The problem often lies in the source: protein-fortified ultra-processed products, which contain added sugars or additives, mask the benefits of natural and healthy protein sources. It is therefore crucial to distinguish raw protein from the processed food in which it is contained.

the sources

  1. 1Morton RW, Murphy KT, McKellar SR, et al. 2018
  2. 2Leidy HJ, Clifton PM, Astrup A, et al. 2015

Claimed by Brad Stanfield. Noli grades the claim, never the person.

Decoded by Noli · July 18, 2026 · the original post

What the graded evidence says

Evidence
B+
Effect
fat-free mass gain (resistance training) and appetite/satiety — +0.30 kg fat-free mass with protein supplementation (95% CI 0.09-0.52), plateau at ~1.62 g/kg/day; higher protein meals reliably increase satiety vs equal-calorie lower-protein meals
Measured on
healthy training adults; weight-loss and weight-maintenance adults

What’s uncertain

More protein past roughly 1.6 g/kg/day doesn't add much for muscle or fullness. The satiety edge is real but modest, not a magic appetite switch.

Brad Stanfield in the Register30 claims graded · solidity 90/100See their record →

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