Skeletal muscle is the most important organ system in the human body for counteracting current health issues, promoting optimal health, and maximizing physical performance.

noli's read

The idea that skeletal muscle is an "endocrine" or "secretory" organ is widely supported by contemporary scientific research. Studies (published reviews and analyses, notably those on "myokines") confirm that muscle communicates with other organs (brain, liver, bones) and plays a crucial role in glucose metabolism and immunity. The term "organ system" is used in scientific literature to highlight this active nature, which goes beyond simple locomotor function. Although muscle is the most abundant tissue, classifying it as "the most important" is an interpretation focused on the prevention of metabolic diseases and healthy aging, rather than an absolute biological hierarchy. There is no single piece of evidence designating one organ as "the most important," as this depends on the physiological context (the heart or brain being equally critical for immediate survival). The statement is therefore a strong clinical perspective rather than an exclusive biological fact.

the sources

1. 1Wu Y, Wang W, Liu T, Zhang D 2017
2. 2Li R, Xia J, Zhang X, et al. 2018