Psychological stress is a major factor that directly alters intestinal permeability (leaky gut), thereby triggering digestive symptoms independently of diet.

noli's read

The concept of the gut-brain axis is widely supported by modern research, confirming that stress influences digestive physiology. Studies (e.g., meta-analyses published in 'Nature Reviews Gastroenterology & Hepatology') show that psychological stress activates the hypothalamic-pituitary-adrenal axis, releasing hormones such as cortisol and CRH, which can effectively increase intestinal permeability in humans. The creator rightly points out that this mechanism is involved in disorders such as irritable bowel syndrome (IBS). However, the use of the term 'leaky gut' remains a complex subject; while the increase in permeability is real under stress, its role as a sole cause of chronic diseases is still debated. The content is scientifically grounded regarding the modulation of the intestinal barrier by the nervous system, although the clinical extent of this effect varies from one individual to another. This does not constitute a dismissal of diet, but rather a relevant piece of additional information.

the sources

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