Our gut microbiota actively communicates with our hormones: a specific set of bacteria (the estrobolome) regulates circulating estrogen levels, while other microbes stimulate the production of intestinal serotonin, influencing inflammation and our mood.

noli's read

The concept of the 'estrobolome'—the bacteria that regulate our estrogens—is scientifically validated by review journals (notably in MDPI) that detail how our microbes influence the assimilation of these hormones. Furthermore, fundamental research (such as work from UCLA) confirms that nearly 90% of our serotonin, the molecule of serenity, is produced in the gut through the stimulation of our bacteria. A recent observational and modeling study published in Cell Reports even shows that certain microbial strains can directly synthesize this molecule. The influence of the gut on overall inflammation and mood is also supported by a robust body of observational evidence and narrative reviews describing the gut-brain axis. However, while these biological links are real, clinical evidence such as randomized controlled trials (RCTs) in humans remains limited for recommending standardized wellness solutions. Presenting these interactions as a simple and immediate lever for acting on hormonal balance is therefore slightly premature, though the scientific path is extremely promising.

the sources

No named source held this one up — that absence is part of the verdict.