Be wary of alleged food 'hacks' and 'secret foods' supposedly capable of naturally boosting GLP-1 to mimic the effects of weight-loss treatments, as these are primarily instances of deceptive marketing.

noli's read

In nutritional physiology, it is well established that certain nutrients naturally stimulate the secretion of GLP-1 by our intestinal cells. Clinical trials (such as those synthesized by the research team at The Ohio State University) show that protein, soluble fiber, and healthy fats trigger this satiety signal after a meal. However, science highlights a significant difference: the GLP-1 our body produces naturally has a half-life of only a few minutes because it is very quickly deactivated by an enzyme in our system, according to the biochemical research of Campbell and Drucker. Conversely, the synthetic molecules used for weight management are specifically modified to resist this deactivation, allowing for infinitely higher concentrations and a longer duration of action. A narrative review published in the scientific journal *Nutrients* further confirms that dietary approaches alone can in no way match the biological potency of these treatments. Presenting certain foods as magical alternatives or 'hacks' is therefore scientifically unfounded. The creator is thus correct in inviting their audience to take a step back from these social media shortcuts.

the sources

1. 1Wilding JPH et al. (STEP 1) 2021
2. 2Jastreboff AM et al. (SURMOUNT-1) 2022
3. 3Jastreboff AM et al. 2023
4. 4Wilding JPH et al. (STEP 1 extension) 2022