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A major nutrition study that lasted 12 months and had over 600 participants comparing low-fat to low-carb was just released. We broke down …

what it claims

A major 12-month study of more than 600 people shows that there is no significant difference in weight loss between a low-fat diet and a low-carb diet.

holds up

This advice is based on the rigorous DIETFITS study (Gardner et al., 2018, published in JAMA), a high-quality randomized clinical trial (RCT).

noli's read

This advice is based on the rigorous DIETFITS study (Gardner et al., 2018, published in JAMA), a high-quality randomized clinical trial (RCT). The researchers demonstrated that both approaches, when emphasizing food quality (whole foods, reduced added sugars, and processed products), produce nearly identical weight loss results. The study is also robust because it refutes the idea that genotype or baseline insulin levels can predict which diet is 'better' for a given individual. The creator remains faithful to the scientific conclusions: the differences observed between the two groups were statistically negligible (about 0.7 kg over one year). Nothing is exaggerated here; the key point is that success lies in sustainability and diet quality, rather than the exclusive restriction of a single macronutrient.

the sources

Claimed by Examine. Noli grades the claim, never the person.

Decoded by Noli · July 18, 2026 · the original post

What the graded evidence says

Evidence: B

Effect: ad libitum energy intake as a function of dietary energy density — lowering dietary energy density consistently reduces spontaneous calorie intake at matched food weight/fullness; body-fat change tracks the resulting energy balance
Measured on: general adults

Energy balance is the driver, but it's affected by many things (satiety, food quality, sleep, activity), so it's not about rigid calorie math. 'Fat-burning' or 'negative-calorie' foods are a myth.

Examine in the Register45 claims graded · solidity 94/100See their record →